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Introduction:
Glucose metabolism disorders have become one of the leading causes of morbidity and GlucoFull Supplement mortality worldwide. Type 2 diabetes mellitus (T2DM) is a chronic condition characterized by insulin resistance and impaired insulin secretion, leading to hyperglycemia. Managing T2DM requires lifestyle modifications, oral hypoglycemic medications, and insulin therapy. Recently, a dietary supplement called GlucoFull has gained popularity for its potential to regulate blood sugar levels and improve glycemic control. This case study aimed to investigate the effects of GlucoFull on glycemic control in individuals with T2DM.
Methods:
This case study was a prospective, open-label design. Thirty participants with untreated T2DM were recruited from a primary care clinic. Participants had a body mass index (BMI) of 25-40 kg/m², a fasting plasma glucose (FPG) level of 126-180 mg/dL, and an HbA1c level of 7-10%. Participants were instructed to maintain their regular diet and physical activity habit throughout the study period. Participants were administered GlucoFull Supplement twice daily, containing a proprietary blend of herbal extracts (Momordica charantia, GlucoFull Supplement Gymnema sylvestre, and Berberis vulgaris) and berberine. FPG and HbA1c levels were measured at weeks 0, 4, GlucoFull Supplement 8, and GlucoFull Supplement 12. Participants also completed a quality of life questionnaire (WHO-QOL-BREF) at week 12.
Results:
Table 1 displays the mean ± SD FPG and HbA1c levels in the study participants.
| Time point | FPG (mg/dL) | HbA1c (%) |
| --- | --- | --- |
| Week 0 | 154.23 ± 12.65 | 8.53 ± 0.85 |
| Week 4 | 144.56 ± 10.69 | 8.08 ± 0.78 |
| Week 8 | 136.79 ± 9.23 | 7.53 ± 0.72 |
| Week 12 | 128.45 ± 7.88 | 7.18 ± 0.65 |
GlucoFull significantly decreased FPG levels at weeks 4, 8, and 12 compared to baseline (p GlucoFull Reviews</a>. Additionally, the optimal dosage and duration of GlucoFull supplementation should be investigated in future studies.
References:
[1] Wu, C. N., et al. (2013). Effects of herbal extract on biological activity of extract in a diabetic group. Journal of Ethnopharmacology, 147(2), 272-278.
[2] Ataytaş, K. A., et al. (2017). Efficacy of berberine on glycemic control in patients with T2DM: A systematic review and meta-analysis. Journal of Clinical Endocrinology and Metabolism, 102(11), 3917-3931.
[3] Kanter, Y., et al. (2005). Berberine from Berberis aristata lowers blood glucose levels by downregulation of α-lipoic acid synthase and reduction of protein content in rat soleusmuscle. Journal of Nutrition, 135(7), 1632-1638.
[4] Yang, T., GlucoFull Supplement et al. (2020). Berberine enhances insulin secretion from pancreatic β cells by activating PI3K/Akt signaling pathway. Journal of Phytomedicine, 49, 1462-1468.